Surface-enhanced Raman scattering (SERS) sensing of nucleic acids

Newly advanced applications of surface-enhanced Raman scattering (SERS) spectroscopy (SERS) are continuously emerging as promising nanotechnological alternatives for rapid, low-cost, sensitive analysis of nucleic acids. In this chapter, we discuss the key concepts of this technique and its rationale of implementation in nucleic acid analysis, illustrating relevant and representative examples from the literature.