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Microwave-assisted multicomponent synthesis of antiproliferative 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones

Authors :
Subham G. Patel
Aday González-Bakker
Ruturajsinh M. Vala
Paras J. Patel
Adrián Puerta
Apoorva Malik
Rakesh K. Sharma
José M. Padrón
Hitendra M. Patel
Source :
RSC Advances. 12:30404-30415
Publication Year :
2022
Publisher :
Royal Society of Chemistry (RSC), 2022.

Abstract

Herein, we demonstrate a simple, rapid and green synthesis of 2,4-dimethoxy-THPQs under microwave irradiation and their antiproliferative activity, in silico ADMET and drug-likeness studies were carried out.

Details

ISSN :
20462069
Volume :
12
Database :
OpenAIRE
Journal :
RSC Advances
Accession number :
edsair.doi...........82e21a6fec86eea3536d0b644f8f97dc
Full Text :
https://doi.org/10.1039/d2ra04669e