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Multifocal Motor Neuropathy with Conduction Blocks During TNF-alpha Antagonist Therapy in a Patient with Spondyloarthropathy
- Source :
- Journal of Rheumatic Diseases. 20:177
- Publication Year :
- 2013
- Publisher :
- Korean College of Rheumatology, 2013.
-
Abstract
- Tumor necrosis factor (TNF)-alpha antagonist has been proven to have benefit for rheumatologic diseases. Because TNF-alpha is not only an important mediator of inflammation in human body, but plays many physiologic roles, it can cause unique adverse effects or complications related to these functions. Adverse effects involving neurological systems, such as Guillain-Barre syndrome, Chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy with conduction blocks (MMNCB), distal symmetric polyneuropathy, and small fibers neuropathy have been previously reported. However, only several cases of infliximab-associated MMNCB are reported. We report a case of MMNCB which developed while treating spondyloarthropathy with infliximab.
- Subjects :
- medicine.medical_specialty
business.industry
Spondyloarthropathy
Antagonist
Inflammation
Chronic inflammatory demyelinating polyneuropathy
medicine.disease
Gastroenterology
Infliximab
Rheumatology
Internal medicine
Medicine
Tumor necrosis factor alpha
medicine.symptom
business
Adverse effect
Multifocal motor neuropathy
medicine.drug
Subjects
Details
- ISSN :
- 22334718 and 2093940X
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Journal of Rheumatic Diseases
- Accession number :
- edsair.doi...........821697564ce8a549cff32ffd63059b7b