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A Possibility of Using Ion-Track Matrices based on Polyesters to Create Artificial Connective Tissue

Authors :
I. V. Koshlan
I.I. Vinogradov
N. A. Koshlan
А.N. Nechaev
Yu. V. Bogdanova
Daria V. Petrova
Source :
Biotekhnologiya. 37:66-71
Publication Year :
2021

Abstract

The cultivation of Chinese hamster fibroblasts (line V79) on ion-track membranes of various polyesters has been tested. Light and electron microscopy were used to take photographs of polyester membranes with fibroblasts grown on them, which indicated the attachment and proliferation of cells on ion-track adhesive surfaces. The greatest survival of fibroblasts was observed on ion-track membranes with a pore diameter of up to 0.5 μ. It was shown that the chemical composition of the track membrane affects the survival and proliferation rate of Chinese hamster fibroblasts. Polyethylene terephtalate and polyethylene naphtalate membranes provided the highest percentage of grown colonies and the greatest proliferation rate of cells. Track-etched polyester membranes can be used to create adhesive surfaces for the cultivation of fibroblasts and the production of artificial connective tissue. Key words: ion-track membranes and technologies, tissue engineering, fibroblasts, burn therapy

Details

ISSN :
25002341 and 02342758
Volume :
37
Database :
OpenAIRE
Journal :
Biotekhnologiya
Accession number :
edsair.doi...........81b7c071331e40ad428f7d67eecc45eb
Full Text :
https://doi.org/10.21519/0234-2758-2021-37-5-66-71