Photointermediates of the Rhodopsin S186A Mutant as a Probe of the Hydrogen-Bond Network in the Chromophore Pocket and the Mechanism of Counterion Switch

Authors :: Istvan Szundi
and Thomas P. Sakmar
James W. Lewis
Elsa C. Y. Yan
Aditi Bhagat
David S. Kliger
Jacqueline Epps
Source :: The Journal of Physical Chemistry C. 111:8843-8848
Publication Year :: 2007
Publisher :: American Chemical Society (ACS), 2007.
Abstract: The role of a specific serine located in the retinylidene chromophore-binding pocket of bovine rhodopsin was investigated to determine its role in the mechanism of receptor photoactivaiton. The S18...

Subjects :: chemistry.chemical_classification
biology
Stereochemistry
Hydrogen bond
Mutant
Chromophore
Photochemistry
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Serine
General Energy
chemistry
Rhodopsin
biology.protein
Physical and Theoretical Chemistry
Counterion
Mechanism (sociology)

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