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Improved and Practical Synthesis of the Integrastatin Core

Authors :
Hideki Kawakami
Kouichi Matsumoto
Yoshiro Yamagiwa
Nozomi Haruna
Source :
Bulletin of the Chemical Society of Japan. 93:1036-1042
Publication Year :
2020
Publisher :
The Chemical Society of Japan, 2020.

Abstract

The new and versatile method for the synthesis of integrastatin core has been developed by the use of o-toluic acid and 2′-hydroxyacetophenone with NaH/sec-BuLi, followed by the reaction of dihydro...

Details

ISSN :
13480634 and 00092673
Volume :
93
Database :
OpenAIRE
Journal :
Bulletin of the Chemical Society of Japan
Accession number :
edsair.doi...........814806f658b9a73631d5590f4024c196
Full Text :
https://doi.org/10.1246/bcsj.20200070