The Effect of Glutamic Acid and Aspartic Acid on Calcium-Containing Stones

Only glutamic acid (Glu) and aspartic acid (Asp) are acidic amino acids and are negatively charged in ordinary human urine (pH 5.5–6.5). These amino acids and oxalate have a carboxyl group and are suspected to act competitively with each other in Ca stone formation. These factors were considered in the present study which was designed to evaluate the effect of Glu and Asp on Ca stone formation.