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Entendendo o conceito PIRO: da teoria à prática clínica - parte 2
- Source :
- Revista Brasileira de Terapia Intensiva. 22:64-68
- Publication Year :
- 2010
- Publisher :
- GN1 Genesis Network, 2010.
-
Abstract
- A sepsis staging system focused on predisposition, insult, host response and organ failure may provide a useful basis for risk stratification. Knowledge on interactions among predisposing factors, insult characteristics and host response might help us to improve our understanding on sepsis pathophysiology and allow more individual therapeutic approach. Recent clinical studies documented the clinical importance of PIRO approach for severity stratification in septic patients in intensive care unit, and also for specific conditions such as community acquired pneumonia and ventilator associated pneumonia , with a good performance for outcome prediction. In this review we describe how this new concept can be used in clinical practice and provide some insights on its usefulness to facilitate the stratification and potential for enrollment in clinical trials of sepsis therapies.
- Subjects :
- medicine.medical_specialty
business.industry
Ventilator-associated pneumonia
General Medicine
Critical Care and Intensive Care Medicine
medicine.disease
Intensive care unit
law.invention
Sepsis
Clinical Practice
Clinical trial
Therapeutic approach
Community-acquired pneumonia
law
Medicine
business
Intensive care medicine
Risk assessment
Subjects
Details
- ISSN :
- 0103507X
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Revista Brasileira de Terapia Intensiva
- Accession number :
- edsair.doi...........8125faa8583a556799b0becbdf68da06