Hepatitis A and Hepatitis E

Hepatitis A and hepatitis E viruses are transmitted enterically. Clinical manifestations range from no symptoms to acute liver failure. Hepatitis E genotypes 3 and 4 affect the human host by digesting infected animal meats such as swine, wild boar, and deer and can rarely cause chronic hepatitis E. For both hepatitis A and E, treatment mainly involves supportive care; however, for hepatitis E, if acute liver failure or chronic hepatitis is suspected, the drug of choice is ribavirin. Vaccines are available for hepatitis A, and hepatitis E vaccines are being developed and undergoing clinical trials.