Organic modification of magnetite nanoparticles for biomedical applications

Magnetite (Fe3O4) nanoparticles such as thermoseeds for hyperthermia and contrast media in magnetic resonance imaging are attracting increasing attention in biomedicine. The organic modification of nanoparticles is an important technique to improve the biological compatibility and drug delivery functions. Also, the addition of organic molecules and the use of hydrogels as a reaction field in Fe3O4 preparation enable controlling the crystalline phase and particle size. In this chapter, the organic modification of Fe3O4 nanoparticles for biomedical applications is reviewed.