Plasma Cortisol, Aldosterone, and Ascorbic Acid Concentrations in Patients with Septic Shock Do Not Predict Treatment Effect of Hydrocortisone on Mortality. A Nested Cohort Study

Authors :: Qiang Li
Naomi E Hammond
David Shi Hao Liu
Carel J. Pretorius
Louise M Burrell
Jacobus P.J. Ungerer
Balasubramanian Venkatesh
Morag J. Young
Sandra L. Peake
David M. Evans
John Myburgh
Simon Finfer
Andrew Rhodes
Jeremy Cohen
John P. R. Moore
Laurent Billot
Brett McWhinney
Manoj Saxena
Rinaldo Bellomo
Dorrilyn Rajbhandari
Colin McArthur
Source :: American Journal of Respiratory and Critical Care Medicine. 202:700-707
Publication Year :: 2020
Publisher :: American Thoracic Society, 2020.
Abstract: Rationale: Whether biomarkers can identify subgroups of patients with septic shock with differential treatment responses to hydrocortisone is unknown.Objectives: To determine if there is heterogene...

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