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ChemInform Abstract: New Strategy for the Synthesis of the Taxane Diterpenes: Formation of the Eight-Membered B-Ring of Taxol by Semi-Pinacol Rearrangement

Authors :
James Tarrant
Philip Pye
Stephen Thom
Timothy J. Donohoe
Louis Diorazio
M. Giles
Philip Magnus
Source :
ChemInform. 27
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

Solvolysis of the neopentyl triflates 14, 25 and 32 resulted in ring expansion of a seven-membered ring into the eight-membered ring required for the synthesis of the taxanes diterpenoids.

Details

ISSN :
09317597
Volume :
27
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........7f1c36f6c48dc13a8103da7f63efff7f
Full Text :
https://doi.org/10.1002/chin.199608206