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T-box RNA gets boxed
- Source :
- Nature Structural & Molecular Biology. 26:1081-1083
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Bacterial T-boxes are regulatory mRNA regions that control the transcription or translation of factors involved in amino acid supply. T-boxes act by directly binding to non-aminoacylated tRNA in response to amino acid starvation. Three studies now capture three-dimensional structures of tRNA–T-box complexes and reveal a set of RNA features that are required for the recognition of specific tRNAs and modulation of gene expression.
- Subjects :
- chemistry.chemical_classification
0303 health sciences
Messenger RNA
Chemistry
RNA
Amino acid
Cell biology
03 medical and health sciences
0302 clinical medicine
T-box
Structural Biology
Transcription (biology)
Transfer RNA
Gene expression
Molecular Biology
030217 neurology & neurosurgery
030304 developmental biology
Subjects
Details
- ISSN :
- 15459985 and 15459993
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Nature Structural & Molecular Biology
- Accession number :
- edsair.doi...........7ed2fd5cdfd18e49163af7a1234ff8d4
- Full Text :
- https://doi.org/10.1038/s41594-019-0340-9