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T-box RNA gets boxed

Authors :
Alexander Serganov
Jacob W. Weaver
Source :
Nature Structural & Molecular Biology. 26:1081-1083
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

Bacterial T-boxes are regulatory mRNA regions that control the transcription or translation of factors involved in amino acid supply. T-boxes act by directly binding to non-aminoacylated tRNA in response to amino acid starvation. Three studies now capture three-dimensional structures of tRNA–T-box complexes and reveal a set of RNA features that are required for the recognition of specific tRNAs and modulation of gene expression.

Details

ISSN :
15459985 and 15459993
Volume :
26
Database :
OpenAIRE
Journal :
Nature Structural & Molecular Biology
Accession number :
edsair.doi...........7ed2fd5cdfd18e49163af7a1234ff8d4
Full Text :
https://doi.org/10.1038/s41594-019-0340-9