Nano Structured Metal Oxides as Potential Sorbents for188W/188Re Generator: A Comparative Study

Nanostructured oxides of Ti, Zr, and Al were synthesized to evaluate their efficacy as sorbent matrices for the preparation of 188W/188Re generator. These oxides, in many respects, can improve the efficiency of the generator by providing better selectivity and enhanced capacity for 188W, which arises from a higher surface area, surface energy, and surface charge, compared to the attributes of conventionally used bulk alumina. The performance of these materials, in the context of preparation of 188W/188Re generators, were compared with respect to sorption capacity for 188W, shelf-life of the generator, purity, and quality of 188Re for radiopharmaceutical applications.