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ChemInform Abstract: A Facile Synthesis of 1,6-Naphthyridin-5(6H)-ones

Authors :
Nagatoshi Nishiwaki
Yoshiki Ohshiro
Mitsuo Komatsu
Source :
ChemInform. 22
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

3-Cyano-2-(phenylethynyl)pyridine (1) was cyclized intramolecularly under acidic conditions to give 1,6-naphthyridin-5(6H) one (2) and 5H-pyrano[4,3-b]pyridin-5-one (4). Pyranopyridine 4 was readily transformed to 2 or naphthyridinone 9 having an alkyl substituent at 6-position

Subjects

Subjects :
chemistry.chemical_classification
chemistry.chemical_compound
chemistry
Pyridine
Substituent
Naphthyridinone
Organic chemistry
General Medicine
Alkyl

Details

ISSN :
09317597
Volume :
22
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........7d8414378a0150bbe772336d1a90761c
Full Text :
https://doi.org/10.1002/chin.199136203
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