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You break it, you fix it: functions for AID downstream of deamination
- Source :
- Nature Immunology. 14:1112-1114
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- In a phosphorylation-dependent positive feedback loop, the cytidine deaminase AID amplifies the generation of double-strand DNA breaks, which shows it can also function downstream of deamination.
Details
- ISSN :
- 15292916 and 15292908
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Nature Immunology
- Accession number :
- edsair.doi...........7d6de64373844d0ecb49e22bc32c31d1
- Full Text :
- https://doi.org/10.1038/ni.2738