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Body Mass Index and patient-reported measures of function, quality of life and treatment toxicity in women receiving adjuvant chemotherapy for breast cancer

Authors :
Kirsten A. Nyrop
Jane Monaco
Sanah Vohra
Allison Deal
William A Wood
Shlomit S Shachar
E Claire Dees
Gretchen G Kimmick
JoEllen C Speca
Hyman B Muss
Publication Year :
2022
Publisher :
Research Square Platform LLC, 2022.

Abstract

Background: This study investigates whether high body mass index (BMI) in women diagnosed with early breast cancer (BC) is associated with patient-reported symptom severity during chemotherapy.Methods: Women with Stage I-III BC completed toxicity reports for 17 side effects during regularly scheduled chemotherapy infusions. Toxicity reports were compared in women with obesity (BMI >=30) versus no obesity (BMI Results: In a sample of 286 patients, Black women comprised 23% of the sample. The obesity rate was 76% among Black patients and 31% among White patients (pConclusions: Among women with early BC, patients with obesity reported higher chemotherapy toxicity as compared to patients without obesity; however, this did not result in differences in treatment completion.

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........7d5302554d4bbee54b9a44b3ad9cfd27
Full Text :
https://doi.org/10.21203/rs.3.rs-1632995/v1