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Platinum nanoparticle-doped multiwalled carbon-nanotube-modified glassy carbon electrode as a sensor for simultaneous determination of atenolol and propranolol in neutral solution
- Source :
- Ionics. 21:1129-1140
- Publication Year :
- 2014
- Publisher :
- Springer Science and Business Media LLC, 2014.
-
Abstract
- In this paper, the simultaneous determination of β-blockers (atenolol (ATN) and propranolol (PRO)) was investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) at platinum nanoparticle-doped multiwalled carbon-nanotube-modified glassy carbon electrode (PtNPs/MWCNTs/GCE) in 0.1 M PBS (pH 7.4) solution. The modifier, PtNP-doped MWCNTs (PtNPs/MWCNTs), was characterized by transmission electron microscopy (TEM) and electrochemical method which showed an excellent character for electrocatalytic oxidization of ATN and PRO. In addition, the experimental parameters such as pH values, the concentration of PtNPs/MWCNTs, and the scan rate were optimized. CV and DPV results show that the β-blockers can be detected selectively and sensitively at modified GCE. Under the optimized condition, the detection limits of ATN and PRO are 1.17 and 0.15 μM (S/N = 3) with the linear ranges of 5.8–116 and 0.2–50 μM, respectively.
- Subjects :
- Horizontal scan rate
Nanotube
Materials science
General Chemical Engineering
General Engineering
General Physics and Astronomy
chemistry.chemical_element
Electrochemistry
Platinum nanoparticles
chemistry
Organic chemistry
General Materials Science
Differential pulse voltammetry
Cyclic voltammetry
Platinum
Chemically modified electrode
Nuclear chemistry
Subjects
Details
- ISSN :
- 18620760 and 09477047
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Ionics
- Accession number :
- edsair.doi...........7d4605c64dd9cacb6f6de420c3cc1c65