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Clear cell carcinoma of the hard palate: A case report
- Source :
- Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 31:113-117
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Clear cell carcinoma (CCC) is a rare malignant tumor that represents less than 1% of all malignant tumors in the salivary glands. The term CCC was officially defined in the fourth edition of the World Health Organization classification of salivary tumors in 2017. Herein, we report a case of CCC arising in the hard palate of an 85-year-old man. The lesion was clinically suspected to be salivary gland tumor, and was resected under general anesthesia. Histopathologically, the tumor consisted of clear cells containing diastase-digestive PAS-positive granules without mucin. Immunohistochemically, the tumor cells were positive for cytokeratin and epithelial membrane antigen, but did not react with myoepithelial differentiation markers. Additional imaging techniques (computed tomography, magnetic resonance imaging, and positron emission tomography) were used to examine the lesion. No metastatic lesions were observed in other regions of the body. Thus, based on the histopathological and immunohistochemical findings and the results of the imaging tests, the tumor was finally diagnosed as a CCC. No evidence of recurrence or metastasis was noted after surgery.
- Subjects :
- Pathology
medicine.medical_specialty
medicine.diagnostic_test
business.industry
Myoepithelial cell
Magnetic resonance imaging
030206 dentistry
medicine.disease
Pathology and Forensic Medicine
Metastasis
Lesion
03 medical and health sciences
Cytokeratin
0302 clinical medicine
medicine.anatomical_structure
Otorhinolaryngology
Positron emission tomography
030220 oncology & carcinogenesis
Clear cell carcinoma
medicine
Surgery
Hard palate
Oral Surgery
medicine.symptom
business
Subjects
Details
- ISSN :
- 22125558
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
- Accession number :
- edsair.doi...........7d20438819a94d1164445bc7a2bc7115