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The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future

Authors :
Andrew D. Campbell
Rubén Haro
Thomas Andrew Brandt
Melodie Christensen
David B. Damon
Ke Wang
Carolina Alhambra
Paul C. Lobben
Jacob M. Janey
J. Eugenio de Diego
Ling Li
Iulia I. Strambeanu
Susana García-Cerrada
Javier Magano
Emma McInturff
Steven M. Mennen
Jack Twilton
David W. C. MacMillan
Fangfang Liu
Jesús Castañón
Matthew A. Zajac
Pablo Garcia-Losada
Sebastien Monfette
Mario Barberis
Alan H. Cherney
Jason M. Stevens
Barbara J. Sitter
Danielle M. Schultz
Ronald J. Post
Simon Berritt
C. Liana Allen
David C. Leitch
Source :
Organic Process Research & Development. 23:1213-1242
Publication Year :
2019
Publisher :
American Chemical Society (ACS), 2019.

Abstract

High-throughput experimentation (HTE) has revolutionized the pharmaceutical industry, most notably allowing for rapid screening of compound libraries against therapeutic targets. The past decade ha...

Details

ISSN :
1520586X and 10836160
Volume :
23
Database :
OpenAIRE
Journal :
Organic Process Research & Development
Accession number :
edsair.doi...........7d057d4265eaefcd550f067f2a336489