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Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism

Authors :
Nian Tong
Jennifer Wong-Roushar
Adrianne Wallace-Povirk
Yesha Shah
Morgan C. Nyman
Jade M. Katinas
Mathew Schneider
Carrie O’Connor
Xun Bao
Seongho Kim
Jing Li
Zhanjun Hou
Larry H. Matherly
Charles E. Dann
Aleem Gangjee
Source :
ACS Pharmacology & Translational Science. 6:748-770
Publication Year :
2023
Publisher :
American Chemical Society (ACS), 2023.

Details

ISSN :
25759108
Volume :
6
Database :
OpenAIRE
Journal :
ACS Pharmacology & Translational Science
Accession number :
edsair.doi...........7c2d99f0e56cb14cc8298ab6d6766d24
Full Text :
https://doi.org/10.1021/acsptsci.3c00020