Synthesis of pyrrolizidine alkaloids via rhodium-catalyzed silylformylation and amidocarbonylation

Authors :: Qingping Zeng
Masakatsu Eguchi
Anna Korda
Iwao Ojima
Source :: Tetrahedron Letters. 34:915-918
Publication Year :: 1993
Publisher :: Elsevier BV, 1993.
Abstract: Rhodium-catalyzed silylformylation and amidocarbonylation are applied to the syntheses of pyrrolizidine alkaloids, (±)-isoretronecanol and (±)-trachelanthamidine, from 5-ethynyl-2-pyrrolidinone.

Subjects :: Bicyclic molecule
Organic Chemistry
chemistry.chemical_element
Primary alcohol
Biochemistry
Catalysis
Formylation
Rhodium
Isoretronecanol
chemistry.chemical_compound
chemistry
Drug Discovery
Pyrrolizidine
Organic chemistry
Trachelanthamidine

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