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The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT): initial aims and impact of the family history of type 1 diabetes mellitus in Japanese children
- Source :
- Pediatric Diabetes. 2:160-169
- Publication Year :
- 2001
- Publisher :
- Hindawi Limited, 2001.
-
Abstract
- The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT) was established in July 1994 with the chief aim to improve the quality of therapy for type 1 diabetes in children, an entity far less common in Japan than in Europe. We proposed four initial research topics: (i) to determine the current status of medical care and glycemic control in Japanese children with type 1 diabetes mellitus; (ii) to standardize the measurement of hemoglobin A1c; (iii) to establish a registry of a large cohort of patients in order to enable prospective studies to improve the quality of therapy for children with type 1 diabetes in Japan; and (iv) to enable participants of the JSGIT to hold a workshop twice annually. We registered a total of 736 patients from 45 hospitals throughout Japan. Intervention via insulin treatment was instituted after 2 yr for those patients whose hemoglobin A1c level was more than 8.1%. The proportion of patients receiving multiple insulin injections increased after intervention; however, average hemoglobin A1c in females remained significantly higher than in males. We identified two forms of diabetes in Japanese children: a rapidly progressive form and a more slowly progressive form. There was a significantly higher prevalence of a family history of diabetes in first-degree relatives in the slowly progressive form. These preliminary findings are the result of the first collaborative study of childhood diabetes in Japan.
- Subjects :
- medicine.medical_specialty
Type 1 diabetes
Pediatrics
business.industry
Endocrinology, Diabetes and Metabolism
Insulin
medicine.medical_treatment
MEDLINE
medicine.disease
Endocrinology
Internal medicine
Diabetes mellitus
Intervention (counseling)
Pediatrics, Perinatology and Child Health
Internal Medicine
medicine
Family history
Prospective cohort study
business
Glycemic
Subjects
Details
- ISSN :
- 1399543X
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Pediatric Diabetes
- Accession number :
- edsair.doi...........7aa881af703a9ec5d2f4e666594261fd