A common intermediate providing syntheses of .PSI.-tabersonine, coronaridine, iboxyphylline, ibophyllidine, vinamidine, and vinblastine

Authors :: William G. Bornmann
Martin E. Kuehne
Source :: The Journal of Organic Chemistry. 57:1752-1760
Publication Year :: 1992
Publisher :: American Chemical Society (ACS), 1992.
Abstract: Generation of the key tetracyclic intermediates 14a,b in six steps (42% overall) and subsequent short reduction, oxidation, and arylation sequences results in total syntheses of the title compounds 8, 9, 10, 11, 12, and 13

Subjects :: chemistry.chemical_classification
chemistry.chemical_compound
Polycyclic compound
Vinamidine
chemistry
Stereochemistry
Organic Chemistry
medicine
Tabersonine
Total synthesis
Coronaridine
Vinblastine
medicine.drug

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