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Modeling residential indoor concentrations of PM 2.5 , NO 2 , NO x , and secondhand smoke in the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air study
- Source :
- Indoor Air. 31:702-716
- Publication Year :
- 2020
- Publisher :
- Hindawi Limited, 2020.
-
Abstract
- Increased outdoor concentrations of fine particulate matter (PM2.5 ) and oxides of nitrogen (NO2 , NOx ) are associated with respiratory and cardiovascular morbidity in adults and children. However, people spend most of their time indoors and this is particularly true for individuals with chronic obstructive pulmonary disease (COPD). Both outdoor and indoor air pollution may accelerate lung function loss in individuals with COPD, but it is not feasible to measure indoor pollutant concentrations in all participants in large cohort studies. We aimed to understand indoor exposures in a cohort of adults (SPIROMICS Air, the SubPopulations and Intermediate Outcome Measures in COPD Study of Air pollution). We developed models for the entire cohort based on monitoring in a subset of homes, to predict mean 2-week-measured concentrations of PM2.5 , NO2 , NOx , and nicotine, using home and behavioral questionnaire responses available in the full cohort. Models incorporating socioeconomic, meteorological, behavioral, and residential information together explained about 60% of the variation in indoor concentration of each pollutant. Cross-validated R2 for best indoor prediction models ranged from 0.43 (NOx ) to 0.51 (NO2 ). Models based on questionnaire responses and estimated outdoor concentrations successfully explained most variation in indoor PM2.5 , NO2 , NOx , and nicotine concentrations.
- Subjects :
- Pollutant
COPD
Environmental Engineering
010504 meteorology & atmospheric sciences
business.industry
Public Health, Environmental and Occupational Health
Air pollution
Building and Construction
Intermediate outcome
respiratory system
010501 environmental sciences
medicine.disease_cause
medicine.disease
complex mixtures
01 natural sciences
Indoor air quality
Environmental health
Cohort
medicine
business
NOx
0105 earth and related environmental sciences
Exposure assessment
Subjects
Details
- ISSN :
- 16000668 and 09056947
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Indoor Air
- Accession number :
- edsair.doi...........792cd7b45eac8350df36724d1f901f62