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Lymphodepletion and tumor burden govern clinical responses in patients with B-cell malignancies treated with autologous, CD19-targeted T cells

Authors :
Renier J. Brentjens
Nicole Lamanna
Michel Sadelain
Isabelle Riviere
Mark G. Frattini
Jae Hong Park
Xiuyan Wang
Robert W. Yeh
M. Davilla
Source :
Journal of Clinical Oncology. 29:2534-2534
Publication Year :
2011
Publisher :
American Society of Clinical Oncology (ASCO), 2011.

Abstract

2534 Background: We have initiated phase I clinical trials treating patients with chemotherapy-refractory chronic lymphocytic leukemia (CLL) (IRB #06-138) and relapsed acute lymphoblastic leukemia ...

Details

ISSN :
15277755 and 0732183X
Volume :
29
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........7902ffb02e5f001750c69c717b5e53cd