A study of methylated glutathione s-transferase 1 (mGSTP1)as a potential plasma epigenetic marker of response to chemotherapy and prognosis in men with castration-resistant prostate cancer (CRPC)

Authors :: Lisa G. Horvath
James Devaney
Kate L. Mahon
Mark D. Chatfield
Gavin Marx
Richard Wykes
Wenjia Qu
Susan J. Clark
R. L. Sutherland
Martin R. Stockler
Michael Boyer
Cheryl L. Paul
Source :: Journal of Clinical Oncology. 29:4603-4603
Publication Year :: 2011
Publisher :: American Society of Clinical Oncology (ASCO), 2011.
Abstract: 4603 Background: GSTP1 is inactivated in >98% of all prostate cancers through aberrant DNA methylation. A urinary mGSTP1 assay has been developed as a diagnostic test for localized PC. Serum mGSTP1...

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