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Processing of kinetic microarray signals

Authors :
Martin Hegner
Thomas Braun
François Huber
Christoph Gerber
Murali Krishna Ghatkesar
Hans Peter Lang
Natalija Backmann
Source :
Sensors and Actuators B: Chemical. 128:75-82
Publication Year :
2007
Publisher :
Elsevier BV, 2007.

Abstract

Measurement of kinetics using microarrays requires adapted experimental analysis for data evaluation and normalization. Here we present a new algorithm based on alignment of data, which solves inconsistencies of current normalization methods utilizing baseline correction. Our results show that this method leads to better data consistency and relative errors four times smaller on average.

Details

ISSN :
09254005
Volume :
128
Database :
OpenAIRE
Journal :
Sensors and Actuators B: Chemical
Accession number :
edsair.doi...........7799c02269ce696d651ad0a5ecae55f1
Full Text :
https://doi.org/10.1016/j.snb.2007.05.031