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Combining Regions of Antibodies
- Source :
- Immunochemistry of Proteins ISBN: 9781461329244
- Publication Year :
- 1979
- Publisher :
- Springer US, 1979.
-
Abstract
- When a mammalian organism is immunized with an antigenic determinant, a highly complex humoral immune response is induced. This consists of a large number of antibodies complementary to the antigenic determinant. Such antibodies may vary in class and subclass. Furthermore, within a single subclass, there are differences in the energy of interaction with which each antibody of the population binds the antigenic determinant. These interactions may be viewed at a single point in time, although the antibodies expressed at any one time in the immune response may be only a fraction of the number that the animal is capable of producing. Certainly, in viewing these antibodies over a period of time, there are shifts in the populations produced after the initial immunization.
Details
- ISBN :
- 978-1-4613-2924-4
- ISBNs :
- 9781461329244
- Database :
- OpenAIRE
- Journal :
- Immunochemistry of Proteins ISBN: 9781461329244
- Accession number :
- edsair.doi...........7781d72cf2ae43a9f6c6f17b56aa1417