Back to Search
Start Over
Reaction of 2-halo-5-nitropyridines with hydroxide ion in dimethyl sulfoxide
- Source :
- The Journal of Organic Chemistry. 45:3097-3100
- Publication Year :
- 1980
- Publisher :
- American Chemical Society (ACS), 1980.
-
Abstract
- Addition of aqueous base to solutions of 2-halc-5-nitropyridines in dimethyl sulfoxide produces a stable substance which forms 2-hydroxy-5-nitropyridine if the molar ratio of hydroxide to pyridine is greater than 2:l. IR and 'H and 13C NMR spectra of the intermediate stable substance indicate that the pyridine ring is cleaved to form this material. An SN(ANRORC) mechanism is proposed for the reaction.
Details
- ISSN :
- 15206904 and 00223263
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- The Journal of Organic Chemistry
- Accession number :
- edsair.doi...........7657e18fecc6cd6da29ba242ea8be7c9