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ChemInform Abstract: Enantioselective Synthesis of Phenyl-ethanolamines Through Application of Chiral Sulfoxide
- Source :
- ChemInform. 41
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- Efficient enantioselective synthesis of (R)- and (S)-enantiomers of 2-(tert-butylamino)-1-(p-methoxyphenyl)-ethanol has been achieved in high enantiomeric excess by using asymmetric sulfoxide as a chiral auxiliary. The present synthetic approach was further extended to the asymmetric synthesis of (R)-salbutamol.
Details
- ISSN :
- 15222667 and 09317597
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........760a2021b06459adcc0085fed28b409a
- Full Text :
- https://doi.org/10.1002/chin.201004069