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ChemInform Abstract: Enantioselective Synthesis of Phenyl-ethanolamines Through Application of Chiral Sulfoxide

Authors :
Aathimanivelu V. Sivakumar
Anand M. Lahoti
Sujata V. Bhat
Source :
ChemInform. 41
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

Efficient enantioselective synthesis of (R)- and (S)-enantiomers of 2-(tert-butylamino)-1-(p-methoxyphenyl)-ethanol has been achieved in high enantiomeric excess by using asymmetric sulfoxide as a chiral auxiliary. The present synthetic approach was further extended to the asymmetric synthesis of (R)-salbutamol.

Details

ISSN :
15222667 and 09317597
Volume :
41
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........760a2021b06459adcc0085fed28b409a
Full Text :
https://doi.org/10.1002/chin.201004069