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ChemInform Abstract: Synthesis and Salidiuretic Activity of 2,3-Dihydro-8-(1-pyrrolyl)-1,2, 4-triazolo(4,3-a)pyridines and 5,6-Dihydro-4H-pyrido(2,3-c)pyrrolo-(1, 2-e)-1,2,5-triazepines

Authors :
Brigitte Bouteau
Jean-Louis Imbs
Mariette Barthelmebs
Max Robba
Jean-Charles Lancelot
Source :
ChemInform. 22
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

Starting from 2-hydrazino-3-(1-pyrrolyl)pyridine 3 a series of 2, 3-dihydro-8-(1-pyrrolyl-1, 2, 4-triazolo[4, 3-a]-pyridines 49-50 and 5, 6-dihydro-4H-pyrido[2, 3-c]pyrrolo[1, 2-e]-1, 2, 5-triazepines 32-42 were synthesized and tested p.o. in rats for salidiuretic and renal vasodilator activity.

Details

ISSN :
09317597
Volume :
22
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........75cd2af2972956a965aa8a269587d53c