Thrombosis and Anticoagulation in Children

Venous thromboembolism (VTE) is being increasingly recognized in the pediatric population as a complication of health care. Estimates of the annual incidence of VTE in the general pediatric population range from 0.14 to 0.21/10,000 children. Risk factors include inherited causes as factor V Leiden mutation, prothrombin 20210, and protein C deficiency and acquired causes as central venous catheters, trauma, and immobilization.