ChemInform Abstract: Design, Synthesis, and Structure-Activity Relationships of a Series of 2-Ar-8-methyl-5-alkylaminoquinolines as Novel CRF1Receptor Antagonists

Authors :: Kunitoshi Takeda
Taro Terauchi
Mitsuhiro Ino
Kogyoku Shin
Minako Hashizume
Masahiro Yonaga
Hisashi Shibata
Source :: ChemInform. 44
Publication Year :: 2013
Publisher :: Wiley, 2013.
Abstract: Novel compounds (VI) are identified as orally active corticotropin-releasing factor 1 (CRF1) receptor antagonists.

Subjects :: endocrine system
Orally active
Design synthesis
Stereochemistry
Chemistry
Crf1 receptor
General Medicine
Receptor
hormones, hormone substitutes, and hormone antagonists
Corticotropin-releasing hormone receptor 1

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