THE THE MICROEMULSION AS A KEY PLAYER IN CONQUERING THE SKIN BARRIER FOR THE AIM OF TRANSDERMAL DELIVERY OF DRUGS: REVIEWING A SUCCESSFUL DECADE

Microemulsion (ME) systems are now considered of the most successful transdermal drug delivery systems. This is due to their nanodroplets size in the one hand and to their composition that enables the use of several mechanistically penetration enhancers in the same formulation on the other hand. This work summarizes the types, properties, and the merits of the use of MEs for transdermal delivery and reviews the successful studies that were performed to deliver several drugs through this important route during the past 10–12 years.