SOLUBLE FORMS OF PD-1 AND PD-L1 IN BLOOD PLASMA OF GASTRIC CANCER PATIENTS AND THEIR ASSOCIATIONS WITH CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF THE DISEASE

Authors :: N Y Sokolov
V V Delektorskaya
N.A. Ognerubov
E. S. Gershtein
N. E. Kushlinskii
V L Chang
Ivan Stilidi
S B Polikarpova
E A Korotkova
Source :: Russian Clinical Laboratory Diagnostics. 65:347-352
Publication Year :: 2020
Publisher :: EKOlab, 2020.
Abstract: Results of comparative ELISA investigation of pretreatment sPD-1 and sPD-L1 content in blood plasma of 100 gastric cancer patients at various disease stages aged 25 to 81 years are presented. Control group included 60 practically healthy donors aged 18 - 68 years. Plasma sPD-L1 concentrations did not differ between gastric cancer patients and control group, and sPD-1 levels were statistically significantly lower in patients than in healthy donors (p

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