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Effect of laser functionalization of titanium on bioactivity and biological response
- Source :
- Applied Surface Science. 525:146492
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- This study proposes Direct Laser Interference Lithography as a highly suitable technique for functionalization titanium surfaces for biomedical applications. DLIL was employed to produce periodic patterns on titanium after two commonly used surface treatments of implantable devices (shot peening and acid etching). The biomedical potential of the proposed method was analyzed using immersion tests in a simulated body fluid solution and cell adhesion tests. After 48 h of immersion surface morphology, the chemical composition and phase structure of the apatite layers deposited on the modified titanium were analyzed. In order to analyze the kinetics of the apatite layer growth, X-Ray Photoelectron Spectroscopy measurements at different soaking times were performed. Cell adhesion tests were performed using human fetal osteoblastic cells (hFOB). The adhered cells were analyzed using confocal and scanning electron microscopies after 48 h of incubation. The formation of biomimetic apatite layers was accelerated on the titanium surface structures after DLIL modification. The periodic titanium patterns induced more uniform and direct cell growth. This effect is mainly connected with the surface properties of the DLIL-modified substrates. The formation mechanism of biomimetic apatite on the textured titanium samples, as well as the compounds created on the surface, are discussed.
- Subjects :
- Materials science
Scanning electron microscope
Simulated body fluid
General Physics and Astronomy
chemistry.chemical_element
02 engineering and technology
010402 general chemistry
Shot peening
01 natural sciences
Apatite
X-ray photoelectron spectroscopy
technology, industry, and agriculture
Surfaces and Interfaces
General Chemistry
021001 nanoscience & nanotechnology
Condensed Matter Physics
0104 chemical sciences
Surfaces, Coatings and Films
chemistry
Chemical engineering
visual_art
visual_art.visual_art_medium
Surface modification
0210 nano-technology
Layer (electronics)
Titanium
Subjects
Details
- ISSN :
- 01694332
- Volume :
- 525
- Database :
- OpenAIRE
- Journal :
- Applied Surface Science
- Accession number :
- edsair.doi...........732b5e28d542c0399d82735c422b7578