Hypoxia inducible factor 1 alpha confers androgen independence in prostate cancer

Authors :: Bibby, B
Tran, M
Yang, L
Lo, F
Warren, A
Shukla, D
Osborne, M
Hadfield, J
Carroll, T
Stark, R
Scott, H
Ramos-Montoya, A
Massie, C
Maxwell, P
West, C
Mills, I
Neal, D
Publication Year :: 2019
Publisher :: Elsevier BV, 2019.
Abstract: Androgen receptor (AR) and hypoxia inducible factor 1a (HIF1a) are transcription factors that promote prostate cancer progression and radioresistance. This study investigated the relationship between the AR and HIF1a signaling pathways.

Subjects :: 32 Biomedical and Clinical Sciences
3211 Oncology and Carcinogenesis
3202 Clinical Sciences
51 Physical Sciences
5105 Medical and Biological Physics

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