Back to Search
Start Over
Synthesis and Properties of a Novel Water-Soluble Lactose-Containing Polymer and Its Cross-Linked Hydrogel
- Source :
- Macromolecules. 30:7063-7068
- Publication Year :
- 1997
- Publisher :
- American Chemical Society (ACS), 1997.
-
Abstract
- A simple and efficient method for the synthesis of lactose-based homopolymers from lactose O-(p-vinylbenzyl)oxime (4) is described. Free radical polymerization of the new oxime monomers proceeded smoothly in an aqueous solution using potassium persulfate (KPS) and N,N,N‘,N‘-tetramethylethylenediamine (TMEDA) as the initiating system and gave water-soluble homopolymers in good yields. These synthetic lactose-based polymers had high molecular weights and narrow polydispersities (Mw/Mn: 1.20−1.35) as determined by size exclusion chromatography, in conjunction with multiangle laser light scattering (SEC−MALLS). The Mark−Houwink equation was obtained as [η] = 2.15 × 10-4Mv0.73. When the monomer was copolymerized with the cross-linking reagent N,N‘-methylenebis(acrylamide) (BisA) (16% mol), hydrogels were formed which swelled as much as 21-fold in deionized water. These gels have potential applications as biocompatible materials.
- Subjects :
- chemistry.chemical_classification
Aqueous solution
Polymers and Plastics
Chemistry
Organic Chemistry
Radical polymerization
Size-exclusion chromatography
Disaccharide
Multiangle light scattering
Potassium persulfate
Polymer
Inorganic Chemistry
chemistry.chemical_compound
Monomer
Polymer chemistry
Materials Chemistry
Subjects
Details
- ISSN :
- 15205835 and 00249297
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Macromolecules
- Accession number :
- edsair.doi...........72991b238cb575995fd44d9d3d1607c9