POST VIRAL FATIGUE SYNDROME IN COVID-19 AND ITS ASSOCIATION WITH INFLAMMATORY MARKERS AMONGST HEALTH CARE WORKERS

Background: Coronavirus contribute to respiratory illness, including severe disease. COVID-19 infection is associated with multiple acute complications including post viral fatigue syndrome. Healthcare workers have a higher rate of exposure to this virus which crippled the healthcare system. Patients acutely infected with SARS-CoV-2, demonstrate elevated inammatory markers. Hence in this study we sought to establish whether patients of SARS-CoV-2 infection remained fatigued post recovery and whether there was a relationship between severe fatigue and inammatory markers. 390 COVID-19 Materials And Methods: positive healthcare workers were studied at Assam Medical College and Hospital from July 2021 to June 2022. Assessment of fatigue was done using the Prole of Fatigue Related Symptoms (PFRS) score. In our study, maximum belong to age group 18-30 ye Results: ars of age (45.64%). Out of 390 cases, 211 (54.10%) were female. 180 (46.2%) had elevated LDH, 209 (53.6%) had elevated CRP. 18 (4.6%) had an SPO2 of < 90% in room air, post viral fatigue syndrome was present in 201 (51.54%) out of which 38(9.75%) had extreme fatigue symptoms, 163(41.79%) had moderate fatigue symptoms. The association between the association between post viral fatigue syndrome and inammatory markers (LDH and CRP) was signicant (p < 0.001). There was a signicant association between inamma Conclusion: tory markers (LDH and CRP) with Post Viral Fatigue Syndrome in COVID-19. . Hence, proper assessment after ruling out other co-existent diseases and using the Prole of Fatigue Related Symptoms (PFRS) score, may help in identifying cases of Post Viral Fatigue Syndrome