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ChemInform Abstract: Cross-Coupling of Aryllithiums with Aryl and Vinyl Halides in Flow Microreactors

Authors :
Jun-ichi Yoshida
Aiichiro Nagaki
Yuya Moriwaki
Naofumi Takabayashi
Suguru Haraki
Akira Kenmoku
Atsushi Hayashi
Source :
ChemInform. 43
Publication Year :
2012
Publisher :
Wiley, 2012.

Abstract

The coupling of aryl bromides with vinyl bromides in a flow microreactor is best performed via Br/Li exchange of the aryl bromide with BuLi, followed by the Pd(OAc)2-catalyzed Murahashi coupling of the lithiated arene with the vinyl bromide.

Details

ISSN :
09317597
Volume :
43
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........71e6169e40df43bfbb2e98aea9caf408