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Ophthalmic manifestations of tuberous sclerosis: a review

Authors :
Shira L. Robbins
Michael Kinori
Nickisa Hodgson
Michael H. Goldbaum
Source :
Clinical & Experimental Ophthalmology. 45:81-86
Publication Year :
2016
Publisher :
Wiley, 2016.

Abstract

Tuberous sclerosis or tuberous sclerosis complex (TSC), one of the phakomatoses, is characterized by hamartomas of the heart, kidney, brain, skin and eyes. Ophthalmologic examinations are required in all cases of TSC. Retinal hamartomas are the most common ocular finding in tuberous sclerosis. The majority of hamartomas are non-progressive; however, lesions with subretinal fluid and progression have been reported. This paper details the genetics, clinical features and ocular findings of TSC and reviews potential therapeutic options for ophthalmic manifestations.

Details

ISSN :
14426404
Volume :
45
Database :
OpenAIRE
Journal :
Clinical & Experimental Ophthalmology
Accession number :
edsair.doi...........71bbfeeb8ade1fc34ac8dba360553036
Full Text :
https://doi.org/10.1111/ceo.12806