One-Pot Enzymatic Synthesis of Enantiopure 1,3-Oxathiolanes Using Trichosporon laibachii Lipase and the Kinetic Model

Authors :: Kuiying Lv
Yuanyuan Zhang
Fengke Yang
Fanye Wang
Qiuxiang Zhao
Sun Yangjian
Wenjie Ren
Hui Tang
Junhong Liu
Source :: Organic Process Research & Development. 24:579-587
Publication Year :: 2020
Publisher :: American Chemical Society (ACS), 2020.
Abstract: The dynamic covalent kinetic resolution was efficiently realized for the synthesis of an enantiopure ((R) -5-acetoxy-1,3-oxathiolan-2-yl)ethyl benzoate (PR) from substrates 2-(phenylmethoxy)acetald...

Subjects :: biology
Kinetic model
010405 organic chemistry
Organic Chemistry
Enzymatic synthesis
010402 general chemistry
01 natural sciences
Ethyl benzoate
0104 chemical sciences
Kinetic resolution
chemistry.chemical_compound
Enantiopure drug
chemistry
Covalent bond
biology.protein
Trichosporon laibachii
Organic chemistry
Physical and Theoretical Chemistry
Lipase

Full Text Access

Tools