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How Actin Tracks Affect Myosin Motors
- Source :
- Advances in Experimental Medicine and Biology ISBN: 9783030380618
- Publication Year :
- 2020
- Publisher :
- Springer International Publishing, 2020.
-
Abstract
- Cellular organization through cytoskeletal trafficking is a process of fundamental importance. Highly specialized systems evolved that enable motors to identify and select the optimal tracks for motility. In this chapter, we examine the profound effect of actin filament networks on myosin motility patterns. We argue that the myosin classes have adaptations that allow them to detect local structural and chemical cues on actin. These cues are often arranged in a coherent manner on actin filament networks, allowing for directed transport over long distances. We identify a number of potentially important cues, ranging from the biochemical states of actin subunits all the way to multi-filament networks and bundles.
Details
- ISBN :
- 978-3-030-38061-8
- ISBNs :
- 9783030380618
- Database :
- OpenAIRE
- Journal :
- Advances in Experimental Medicine and Biology ISBN: 9783030380618
- Accession number :
- edsair.doi...........6ff93954ae4f77d3aa844bde124d6ee2