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Natural Product-Based Drug Discovery in Africa: The Need for Integration into Modern Drug Discovery Paradigms

Authors :
Eric M. Guantai
Kelly Chibale
Source :
Drug Discovery in Africa ISBN: 9783642281747
Publication Year :
2012
Publisher :
Springer Berlin Heidelberg, 2012.

Abstract

A myriad of infectious diseases continue to cause the death and suffering of millions of people in sub-Saharan Africa. Efforts to mitigate this suffering involve, among others, concerted efforts at discovering and developing new and more efficacious therapies for these diseases. To support these efforts, the full potential of Africa’s rich and vibrant biodiversity as a source of lead compounds and drug candidates needs to be harnessed. This would require a complete reevaluation of how natural product drug discovery is conducted on the continent, and in this chapter, we describe some of the components that could underpin this proposed transformation.

Details

ISBN :
978-3-642-28174-7
ISBNs :
9783642281747
Database :
OpenAIRE
Journal :
Drug Discovery in Africa ISBN: 9783642281747
Accession number :
edsair.doi...........6f18b5df525038a8136106233d76a3ee
Full Text :
https://doi.org/10.1007/978-3-642-28175-4_5