Stereoselective Synthesis of <font>β</font>-Amino Ketones via Direct Mannich-Type Reaction Catalyzed with

At room temperature, and efficiently catalyze the direct Mannich-type reaction of varieties of in situ–generated aldimines using aldehydes and anilines with ketones in a three-component reaction under solvent-free conditions. The reaction proceeds rapidly and affords the corresponding β-amino ketones in good to high yields with good to excellent stereoselectivity. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency.