P(NMe2)3-promoted ortho-selective arylation of phenols with diaryliodonium triflates via rhodium catalysis

Authors :: De-Yin Wang
Zhong-Yi Ma
Qi-Sheng Liu
Jin-Fei Yang
Mengchun Ye
Source :: Tetrahedron. 73:3591-3595
Publication Year :: 2017
Publisher :: Elsevier BV, 2017.
Abstract: Rh-catalyzed ortho-selective arylation of free phenol with diaryliodonium triflates to widely existed phenol-containing biaryls have been developed. The use of P(NMe2)3, tBuOLi and CH3CN proved to be critical for the ortho-selectivity of this reaction.

Subjects :: 010405 organic chemistry
Organic Chemistry
chemistry.chemical_element
010402 general chemistry
01 natural sciences
Biochemistry
0104 chemical sciences
Catalysis
Rhodium
chemistry.chemical_compound
chemistry
Drug Discovery
Organic chemistry
Phenols
Free phenol

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