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Correlation of observed-to-expected total fetal lung volume with intrathoracic organ herniation on magnetic resonance imaging in fetuses with isolated left-sided congenital diaphragmatic hernia
- Source :
- Ultrasound in Obstetrics & Gynecology. 46:162-167
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- Objectives To assess using fetal magnetic resonance imaging (MRI) the relationship between the position of the stomach as well as the volume of herniation of organs into the thorax, and the observed-to-expected total fetal lung volume (o/e-TFLV), as a measure of pulmonary hypoplasia, in fetuses with isolated left-sided congenital diaphragmatic hernia (LCDH). Methods This was a single-center retrospective study using archived MR images from fetuses > 20 weeks' gestation evaluated for isolated LCDH over an 11-year period between July 2002 and September 2013. We retrieved data on the gestational age at MRI, o/e-TFLV and liver position. Images were also reviewed by a single operator to determine retrospectively the position of the stomach as well as the proportion of the total thorax volume occupied by the herniated fetal liver, stomach and other viscera. Following confirmation of reproducibility, we assessed the correlation of intrathoracic organ volumes and stomach position with o/e-TFLV. Results The study included 205 fetuses which underwent a total of 259 MR examinations. The reproducibility of organ volume measurements was excellent (intraclass correlation coefficient range, 0.928–0.997). The average time spent to obtain intrathoracic organ volumes ranged from 2.28 to 5.13 min. Of all herniated organ-to-thoracic volume ratios, the liver-to-thoracic volume ratio had the strongest correlation with o/e-TFLV (ρ = −0.429, P
- Subjects :
- Thorax
Fetus
medicine.medical_specialty
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
Stomach
Obstetrics and Gynecology
Gestational age
Congenital diaphragmatic hernia
Magnetic resonance imaging
General Medicine
medicine.disease
Pulmonary hypoplasia
medicine.anatomical_structure
Reproductive Medicine
medicine
Radiology, Nuclear Medicine and imaging
Lung volumes
Radiology
business
Subjects
Details
- ISSN :
- 09607692
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- Ultrasound in Obstetrics & Gynecology
- Accession number :
- edsair.doi...........6e4da0eab6ce6ff46a180fae9b1fe48e
- Full Text :
- https://doi.org/10.1002/uog.14701