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Remission of diabetic nephropathy in type 2 diabetic Asian population: role of tight glucose and blood pressure control
- Source :
- European Journal of Clinical Investigation. 41:870-878
- Publication Year :
- 2011
- Publisher :
- Wiley, 2011.
-
Abstract
- Eur J Clin Invest 2011; 41 (8): 870–878 Abstract Background Asian has higher prevalence of diabetic nephropathy (DN) and end-stage renal disease when compared to Caucasian. No study to date has evaluated whether multifactorial intervention was associated with remission of microalbuminuria in type 2 diabetic Asian population. We evaluated the effect of tightly controlling multiple factors on the remission of DN in type 2 diabetic Chinese with microalbuminuria. Materials and methods A longitudinal cohort study was collected 587 type 2 diabetic patients with microalbuminuria. Cohort members received intensified treatment to meet the following ADA recommended goals: HbA1c 40 mg dL−1 for men and > 50 mg dL−1 for women. Remission of microalbuminuria was defined as shift of albumin–creatinine ratio from mircoalbuminuria to normoalbuminuria. Results During the 4·5-year period, 210 (35·8%) patients achieved remission to normoalbuminuria. A significant association was found between the achievement of ADA goals, including HbA1c
- Subjects :
- medicine.medical_specialty
education.field_of_study
business.industry
Clinical Biochemistry
Population
Hazard ratio
General Medicine
Type 2 diabetes
medicine.disease
Biochemistry
Surgery
Diabetic nephropathy
Internal medicine
Diabetes mellitus
Cohort
medicine
Albuminuria
Microalbuminuria
medicine.symptom
education
business
Subjects
Details
- ISSN :
- 00142972
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- European Journal of Clinical Investigation
- Accession number :
- edsair.doi...........6dad92de0fec436941a9837e07a4d309
- Full Text :
- https://doi.org/10.1111/j.1365-2362.2011.02479.x