Confirmatory analysis to determine associations between platinum-sensitivity, molecular signature of combined tumor suppressor defects and aggressive variant prostate carcinomas (AVPC)

Authors :: Timothy C. Thompson
Paul G. Corn
Haidee Chancoco
Lianchun Xiao
Elsa M. Li Ning Tapia
Christopher J. Logothetis
Eleni Efstathiou
Anh Hoang
Ana Aparicio
Elisabeth I. Heath
Patricia Troncoso
Source :: Journal of Clinical Oncology. 34:5020-5020
Publication Year :: 2016
Publisher :: American Society of Clinical Oncology (ASCO), 2016.
Abstract: 5020Background: Clinically defined AVPC is associated with platinum-sensitivity and a molecular profile of combined (≥2) alterations in PTEN, Tp53 and/or RB1 (Aparicio et al. Clin Cancer Res 2013;1...

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